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Monday, December 14, 2009

New research finds limits to the effectiveness of opioids

Once formed, the habits are very difficult to break.It seems easier to go after,before and Don't change anything. This can become a serious problem when science will have a way habits. If you look at the world of adverts and print media, you'll see a sure-fire opioids are recommended medicines used to treat pain, no matter what the pain. And engage in a venerable tradition of the slogan,"Beecham's Pills cure for all problems ".The idea of a miracle drug - one pill to rule them all, as the Dark Lord of Mordor could say - has been around since the beginning of time.This is fair play that marketers use when speaking to the public, but the same thinking has become a Training manuals for the medical profession. Student doctors to sit in lectures and you hear the same story that opioids are the first line of defense. When you have a source of prescriptions in the group believe that the way is almost impossible to break.

Monitoring and review process carried out after the medicine is released on the market to catch any unexpected side effects. If evidence of problems occur,the FDA can require the manufacturer to change the warnings on the label or in the worst case, remove the drug from the market. But monitoring is not designed to stick to medicines that are ineffective. If anyone does not have an adverse reaction when taking it,no report has been registered by the FDA. It's safe so who cares whether it works.All of this brings us to Cochrane Collaboration. This is a non-profit group, which researchers go through and analyze the current published medical research to see whether a consistent pattern - which may not be shown in one clinical study, which was attended by two hundred participants can identify when you compile the results of different trials, each of the fifteen with two hundred participants.Cochrane,two recently published reports showed that opioids should not routinely to patients, even severe pain in the hip and knee osteoarthritis.

In both reports, independent of the conclusions were that harmful side effects and the greater the benefits tramadolAs the leader of opioids,was no more effective than the most powerful anti-inflammatory drugs. The first report on the consolidated results of the ten o'clock studies included a total of more than 2250 participants and found that there was little pain and little to improve mobility.At higher doses,one of the twelve participants experienced adverse side effects.The second report on the consolidated results of eleven trials,1020 participants and found little difference in the effectiveness of tramadol and placebo.This leads to somewhat contradictory conclusion. That doctors should not routinely prescribe opioids to treat hip and knee osteoarthritis. Should be careful discussion of treatment options including weight loss, physical therapy and exercise, and a detailed explanation of any adverse side effects can be expected. This new research does not change the general acceptance as an effective analgesic tramadol. It just confirms that there is no such thing as one piece to improve all the problems.

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